Publications

  1. K. Kahveci, M.B. Düzgün, A.E. Atis, A. Yılmaz, A. Shahraki, B. Coskun, S. Durdagi & N. Birgül Iyison:“ Discovering allatostatin type-C receptor specific agonists“. Nat. Commun 15, 3965 2024 https://doi.org/10.1038/s41467-024-48156-w
  2. Birgül Iyison, N., Abboud, C., Abboud, D., Abdulrahman, A. O., Bondar, A.-N., Dam, J., Georgoussi, Z., Giraldo, J., Horvat, A., Karoussiotis, C., Paz-Castro, A., Scarpa, M., Schihada, H., Scholz, N., Güvenc Tuna, B., & Vardjan, N. (2024). ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system. British Journal of Pharmacology, 1–33. https://doi.org/10.1111/bph.16389
  3. Ferdows Afghah, Necla Birgul Iyison, Ali Nadernezhad, Ahmet Midi, Ozlem Sen, Burcu Saner Okan, Mustafa Culha, and Bahattin Koc:" 3D Fiber Reinforced Hydrogel Scaffolds by Melt Electrowriting and Gel Casting as a Hybrid Design for Wound Healing" Advanced Healthcare Materials, 2022, 2102068, doi: 10.1002/adhm.202102068 
  4. Serdar Durdagi, Muge Didem Orhan, Busecan Aksoydan, Seyma Calis, Berna Dogan, Kader Sahin, Aida Shahraki, Necla Birgül Iyison, and Timucin Avsar: „Screening of Clinically Approved and Investigation Drugs as Potential Inhibitors of SARS-CoV-2: A Combined in silico and in vitro Study" Molecular Informatics, 2021 doi.org/10.1002/minf.202100062 
  5. Aslan T, Yenenler-Kutlu A, Gerlevik U, Aktugülu Zeybek Ac, Kiykim E, Sezerman OU, Birgul Iyison N: "Identifying and elucidating the roles of Y198N and Y204F mutations in the PAH enzyme through molecular dynamic simulations." J Biomol Struct Dyn. 2021 May 10:1-12. doi: 10.1080/07391102.2021.1921619
  6. Shahraki, A., Isbilir, A., Dogan, B., Lohse, M.J., Durdagi, S., Birgul Iyison, N: "Structural and Functional Characterization of Allatostatin Receptor Type-C of Thaumetopoea pityocampa, a Potential Target for Next-Generation Pest Control Agents". J Chem Inf Model. 2021 Jan 21. doi: 10.1021/acs.jcim.0c00985 
  7. Birgul Iyison, N., Shahraki, A., Kahveci, K., Duzgun, M.B., Gun, G: "Are Insect GPCRs Ideal Next-Generation Pesticides: Opportunities and Challenges". FEBS J. 2021 Jan 8.  doi: 10.1111/febs.15708. 
  8. Birgul Iyison, N., Devlet Kilickap, B., Duan Sahbaz, B., Vardar, B., Guclu, B: "Distribution and mRNA expression of nAChRs in the rat S1 and M1 cortices after electrical stimulation of the basal forebrain". Turkish Neurosurgery, 2021 Jan 07. doi: 10.5137/1019-5149.JTN.31865-20.3
  9. Isbilir, A., Duan Sahbaz, B., Tuncgenc, G., Bünemann, M., Lohse, M.J., Birgul-Iyison, N:"Pharmacological Characterization of the Stick Insect Carausius morosus Allatostatin C Receptor with Its Endogenous Agonist". ACS Omega, 2020 Dec. DOI.10.1021/acsomega.0c03382
  10. Necla Birgul Iyison, Merve Gizem Sinmaz, Burcin Duan Sahbaz, Aida Shahraki, Busecan Aksoydan, Serdar Durdagi:"In silico characterization of adipokinetic hormone receptor and screening for pesticide candidates against stick insect, Carausius morosus", Journal of Molecular Graphics and Modelling (2020) 107720, DOI.org/10.1016/j.jmgm.2020.107720
  11. Aida Shahraki, Yanying Yu, Zeynep Melis Gul, Chunguang Liang, Necla Birgul Iyison: "Whole Genome Sequencing of Thametopoea pityocampa Revealed Putative Pesticide Targets", Genomics 112 (2020) 4203–4207, DOI.org/10.1016/j.ygeno.2020.07.017
  12. Duan Sahbaz, B., Birgül İyison, N: Prediction and expression analysis of G protein-coupled receptors in the laboratory stick insect, Carausius morosus. Turkish Journal of Biology, 43, 77-88, DOI.10.3906/biy-1809-27, 2019
  13. İzzet Akiva, Necla Birgül Iyison:"Identification of IFITM3 and MGAT1 as novel interaction partners of BRI3 by Yeast Two-Hybrid Screening",  Turkish Journal of Biology, DOI.10.3906/biy-1805-47, 2018
  14. İ. Even, İ. AKİVA, N. Birgül Iyison:"In vivo RNAi mini-screen in Drosophila cancer model reveals novel potential Wnt targets in liver cancer", Turkish Journal of Gastroenterology, DOI.10.5152/tjg.18241, 2018
  15. Akiva I. and N. Birgül Iyison: MGAT1 is a novel transcriptional target of Wnt/β catenin signaling pathway BMC Cancer 18:60 DOI.org/10.1186/s12885-017-3960-7, 2018
  16. Burcin Duan Sahbaz, Osman Ugur Sezerman, Hamdi Torun & Necla Birgül Iyison: Ligand binding pocket of a novel Allatostatin receptor type C of stick insect, Carausius morosus
. Scientific Reports, 7:41266, DOI: 10.1038/srep41266, 2017
  17. Ayaz Najafov, Tuncay Şeker, İpek Even, Gerta Hoxhaj, Osman Selvi, Duygu Esen Özel, Ahmet Koman and Necla Birgül-İyison: Wnt/beta-Catenin pathway regulates transcription of actin-regulatory protein MENA, PLoS ONE, Volume 7, Issue 5, e37013, DOI:10.1371/journal.pone.0037013, 2012 
  18. Kavak E., Najafov A., Ozturk N., Seker T., Cavusoglu K., Aslan T., Duru A.D., Saygili T., Hoxhaj G., Hiz M.C., Ozer-Unal D., Birgul-Iyison N., Ozturk M., Koman A. „Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and promoter analysis: Identification of BRI3 and HSF2 as novel targets".
Cellular Signalling,  Vol. 22, pp. 1523-1535 DOI:10.1016/j.cellsig.2010.05.021, 2010
  19. Isler C., Tanriverdi T , Kavak E., Sanus G.Z., Ulu M.O., Erkanlı G., Koman A., Birgül-Iyison N., Uzan M. "Prenatal Expressions of Hyperpolarization Cyclic-Nucleotide-Gated Channel (HCN) Genes in Dysplastic Hippocampi in Rats", Türkish Neurosurgery 2008, Vol:18, No.4, 327-335. (PMID:19107678)
  20. Kreienkamp HJ, Larusson HJ, Witte I, Roeder T, Birgul N, Honck HH, Harder S, Ellinghausen G, Buck F, Richter D. "Functional annotation of two orphan G-protein-coupled receptors, Drostar1 and -2, from Drosophila melanogaster and their ligands by reverse pharmacology". J Biol Chem. 2002 Oct 18;277(42):39937-43. Epub 2002 Aug 6. DOI:10.1074/jbc.M206931200
  21. Auerswald L, Birgul N, Gade G, Kreienkamp HJ, Richter D. "Structural, functional, and evolutionary characterization of novel members of the allatostatin receptor family from insects". Biochem Biophys Res Commun. 2001 Apr13;282(4):904-9. DOI:10.1006/bbrc.2001.4659
  22. Birgul N, Weise C, Kreienkamp HJ, Richter D."Reverse physiology in drosophila: identification of a novel allatostatin-like neuropeptide and its cognate receptor structurally related to the mammalian somatostatin/galanin/opioid receptor family". EMBOJ:18(21):5892–5900. DOI:10.1093/emboj/18.21.5892,1999
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  24. Book Chapters:
  25. Duan Sahbaz B., Birgül Iyison N. "Ligands"  Chapter: Neuropeptides as Ligands of GPCRs; In Tech Open Science, 2018