Tolga Aslan

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(0212) 359 7566

Ph.D.: Since 2014
Boğaziçi University, Molecular Biology and Genetics, Istanbul, Turkey

M.Sc.: 2006 – 2009
Boğaziçi University, Molecular Biology and Genetics, Istanbul, Turkey

B.Sc.: 2002 - 2006
Boğaziçi University, Molecular Biology and Genetics, Istanbul, Turkey

Project Keywords: 

PKU, Gene therapy

Techniques: 

Primary tissue culture, induced pluripotent stem cells, 2D  gel  electrophoresis, mass  spectrometry, CRISPR-Cas9

Project Summary: 

Genetic analysis of rare inherited metabolic diseases in Turkish patients and development of personalized gene-therapy systems using primary tissue culture, animal models and Cas9 system.

Publications: 

Kavak E, Najafov A, Ozturk N, Seker T, Cavusoglu K, Aslan T, Duru AD, Saygili T, Hoxhaj G, Hiz MC, Unal DO, Birgül-Iyison N, Ozturk M, Koman A. (2010). Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and  promoter  analysis:  Identification  of  BRI3  and  HSF2  as  novel  targets. Cellular Signaling. 22 (10), 1523-35.
Najafov A, Aslan T, Koman A. (2009). Wnt/β–Catenin Pathway Regulates Transcription of Actin – Regulatory Protein Mena. 4. Eortc Pathobiology Group Annual Meeting & 1. International Multidisciplinary Cancer Research Congress – Antalya
Kavak E, Najafov A, Ozturk N, Seker T, Cavusoglu K, Aslan T, Duru AD, Saygili T, Hoxhaj G, Hiz MC, Unal DO, Birgül-Iyison N, Ozturk M, Koman A. (2005). Identification of novel genes that are differentially expressed in ß-catenin/TCF4 signaling-activated hepatocellular carcinoma cells. Proceedings of the AACR-NCI- EORTC International Conference on Molecular Targets and Cancer Therapeutics, Pennsylvania USA

Currently Teaching: 

BIO342 Physiology laboratory